The Silent Sway of Splicing by Synonymous Substitutions
نویسندگان
چکیده
منابع مشابه
Forbidden synonymous substitutions in coding regions.
In the evolution of highly conserved genes, a few "synonymous" substitutions at third bases that would not alter the protein sequence are forbidden or very rare, presumably as a result of functional requirements of the gene or the messenger RNA. Another 10% or 20% of codons are significantly less variable by synonymous substitution than are the majority of codons. The changes that occur at the ...
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Table S6: Patterns of synonymous and nonsynonymous substitutions
We compared the frequencies of non-synonymous, synonymous and non-protein coding SNPs in the House Finch and poultry populations by comparing three groups of SNPs. The first type were polymorphisms that likely arose in the House Finch MG lineage, as they are fixed in the poultry MG strains but are polymorphic amongst the House Finch ones. The second group are those SNPs that likely arose in the...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2015
ISSN: 0021-9258
DOI: 10.1074/jbc.m115.684035